TY  - JOUR
A1  - Gierer, Alfred
A1  - Berking, S.
A1  - Bode, H.
A1  - David, C. N.
A1  - Flick, K.
A1  - Hansmann, G.
A1  - Schaller, H.
A1  - Trenkner, E.
T1  - Regeneration of hydra from reaggregated cells
N2  - Aggregates of previously isolated cells of Hydra are capable, under suitable solvant conditions, of regeneration forming complete animals. In a first stage, ecto- and endodermal cells sort out, producing the bilayered hollow structure characteristic of Hydra tissue; thereafter, heads are formed (even if the original cell preparation contained no head cells), eventually leading to the separation of normal animals with head, body column and foot. Hydra appears to be the highest type of organism that allows for regeneration of the entire structure from random cell aggregates. The system is particularly useful for studying cell interactions, tissue polarity, pattern formation, and cell differentiation.
KW  - hydra
KW  - regeneration
KW  - cell aggregates
KW  - sorting out
KW  - head formation
KW  - polarity
Y1  - 2006
UR  - https://edoc.bbaw.de/frontdoor/index/index/docId/186
UR  - https://nbn-resolving.org/urn:nbn:de:kobv:b4360-1001036
UR  - http://edoc.bbaw.de/oa/articles/reeEp5S9Slnc/PDF/233pnfxhaZDCs.pdf
ER  -