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  • Gierer, Alfred (1)
  • Schramm, G. (1)

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Infectivity of ribonucleic acid from tobacco mosaic virus (1956)
Gierer, Alfred ; Schramm, G.
Upon separation of the protein from the nucleic acid component of tobacco mosaic virus by phenol, using a fast and gentle procedure, the nucleic acid is infective in assays on tobacco leaves. A series of qualitative and quantitative control experiments demonstrates that the biological activity cannot depend on residual proteins in the preparation, but is a property of isolated nucleic acid which is thus the genetic material of the virus.
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