Regeneration of hydra from reaggregated cells
- Aggregates of previously isolated cells of Hydra are capable, under suitable solvant conditions, of regeneration forming complete animals. In a first stage, ecto- and endodermal cells sort out, producing the bilayered hollow structure characteristic of Hydra tissue; thereafter, heads are formed (even if the original cell preparation contained no head cells), eventually leading to the separation of normal animals with head, body column and foot. Hydra appears to be the highest type of organism that allows for regeneration of the entire structure from random cell aggregates. The system is particularly useful for studying cell interactions, tissue polarity, pattern formation, and cell differentiation.
| Verfasserangaben: | Alfred Gierer, S. Berking, H. Bode, C. N. David, K. Flick, G. Hansmann, H. Schaller, E. Trenkner |
|---|---|
| URN: | urn:nbn:de:kobv:b4360-1001036 |
| URL: | http://edoc.bbaw.de/oa/articles/reeEp5S9Slnc/PDF/233pnfxhaZDCs.pdf |
| Dokumentart: | Wissenschaftlicher Artikel (in einer Zeitschrift) |
| Sprache: | Englisch |
| Datum der Veröffentlichung (online): | 07.11.2006 |
| Veröffentlichende Institution: | Berlin-Brandenburgische Akademie der Wissenschaften |
| Datum der Freischaltung: | 07.11.2006 |
| Freies Schlagwort / Tag: | cell aggregates; head formation; hydra; polarity; regeneration; sorting out |
| Quelle: | Nature / New biology ; 239, S. 98-101 |
| Institute: | BBAW / Veröffentlichungen von Akademiemitgliedern |
| DDC-Klassifikation: | 5 Naturwissenschaften und Mathematik / 50 Naturwissenschaften / 500 Naturwissenschaften und Mathematik |
