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From exclusion to inclusion : improving clinical research in vulnerable populations ; memorandum
(2014)
Therapeutic care for vulnerable populations – meaning patient groups such as underage children and the mentally ill that have limited or no capacity for giving informed consent – is severely lacking. Thus, for example, a great portion of pharmaceuticals used in the treatment of children and youth have not been specifically designed for these groups, which often results in side effects that are disproportionate to those associated with such medicines when used by adults. Moreover, vulnerable populations are at times faced with having no therapies at all for some of their ailments, such that children and dementia sufferers, for example, are often considered to be “therapeutic orphans”. It is therefore urgent that clinical research be carried out among vulnerable populations in order to improve their therapeutic possibilities. The Clinical Research on Vulnerable Populations Research Group – a cooperative effort between the Berlin-Brandenburg Academy of Sciences and Humanities (Berlin, Germany) and the European Academy of Technology Assessment (Bad Neuenahr, Germany) – has set itself the task of analyzing the state of clinical research on vulnerable populations so as to be able to develop suggestions for improving future research of this kind. The results of this work are presented in the following memorandum, which seeks to portray the state-of-the-art in this domain while also assessing the strengths and weaknesses of contemporary ethical and medical perspectives related to it. The memorandum is primarily oriented towards those in the relevant scientific disciplines who can benefit from obtaining an informed consensus regarding the current state of the discussions taking place around this topic.
Der Fachkräftemangel in Mathematik, Informatik, Naturwissenschaften und Technik (MINT) erweist sich immer mehr als Hemmnis für den Hochtechnologiestandort Deutschland. Für eine nachhaltige Sicherung des Fachkräftebedarfs ist eine attraktive MINT-Bildung Voraussetzung. Zudem stellt sich in einer Gesellschaft, die von Natur- und Technikwissenschaften geprägt ist, die Notwendigkeit, allen Menschen ein entsprechendes Grundverständnis zu vermitteln. Wissenschaft und Politik sind gefordert, didaktisch wirksame und für junge Menschen attraktive Konzepte für eine MINT-Bildung zu entwickeln und umzusetzen. Einerseits, um begabte junge Menschen gezielt zu fördern, andererseits,um eine basale MINT-Allgemeinbildung im Schulsystem zu verankern. Der Sammelband fasst die Ergebnisse einer interdisziplinären Arbeitsgruppe der Berlin-Brandenburgischen Akademie der Wissenschaften (BBAW) zusammen und analysiert die Ursachen für den mangelnden Erfolg von MINT-Initiativen in Deutschland und Europa, dokumentiert erfolgreiche Modellprojekte und zeigt Lösungswege für die Bildungs- und Wissenschaftspolitik auf. Ergänzt werden diese Beiträge mit den Erfahrungen engagierter Initiatoren von namhaften Modellprojekten.
Der Fachkräftemangel in Mathematik, Informatik, Naturwissenschaften und Technik (MINT) erweist sich immer mehr als Hemmnis für den Hochtechnologiestandort Deutschland. Für eine nachhaltige Sicherung des Fachkräftebedarfs ist eine attraktive MINT-Bildung Voraussetzung. Zudem stellt sich in einer Gesellschaft, die von Natur- und Technikwissenschaften geprägt ist, die Notwendigkeit, allen Menschen ein entsprechendes Grundverständnis zu vermitteln. Wissenschaft und Politik sind gefordert, didaktisch wirksame und für junge Menschen attraktive Konzepte für eine MINT-Bildung zu entwickeln und umzusetzen. Einerseits, um begabte junge Menschen gezielt zu fördern, andererseits,um eine basale MINT-Allgemeinbildung im Schulsystem zu verankern. Der Sammelband fasst die Ergebnisse einer interdisziplinären Arbeitsgruppe der Berlin-Brandenburgischen Akademie der Wissenschaften (BBAW) zusammen und analysiert die Ursachen für den mangelnden Erfolg von MINT-Initiativen in Deutschland und Europa, dokumentiert erfolgreiche Modellprojekte und zeigt Lösungswege für die Bildungs- und Wissenschaftspolitik auf. Ergänzt werden diese Beiträge mit den Erfahrungen engagierter Initiatoren von namhaften Modellprojekten.
Over millennia human well-being has benefited from ecosystems, not only through tangible goods, but also through intangible assets known as cultural ecosystem services. Despite growing research over the last decade, cultural services assessment still remains arbitrary and is largely limited to marketable services such as tourism. Evident difficulties in standardizing definitions and measurements have challenged cultural services accounting in decision making processes. However, the imminent formation of the Intergovernmental Platform on Biodiversity and Ecosystem Services offers an opportunity to counterbalance this misrepresentation by establishing a scientific basis for consistently assessing cultural services. In that regard, the current review intends to facilitate discussion investigating the current state of cultural services accounting by offering an appraisal of existing evidence regarding cultural services indicator quality. The current review builds on scientifically recognized frameworks to develop a holistic understanding of how cultural services indicators are conceived within ecosystem services research. Among the measures found, benefit indicators were most frequently used for assessing inspirational, educational and recreational services. A broad variety of methods for accounting cultural services was found, mainly due to the varied aims of the studies. Most of the cultural services indicators were deficient concerning their clarity of definitions, purposes and understanding of the processes to be measured and referring only marginally to tradeoffs and bundles with other services. Only 17% performed multitemporal assessments and 23% used spatially explicit information. It seems that cultural services indicators quality could be greatly enhanced by investing more effort towards involving relevant stakeholders in conceptualization and communication phases, using participatory mapping tools to enhance visibility.
This study explores the potential of historical maps to detect, measure and monitor changes of trees outside forests. The main goal is to assess local-level changes of scattered trees and orchards and their land-use determinants in two areas in Southern Germany between 1901/1905 and 2009. Firstly, overall landscape changes are recorded. Secondly, the spatial-temporal trajectories of scattered trees and their land-use determinants are identified. Thirdly, changes in quantity and fragmentation patterns of traditional orchards are analyzed in their relationship to overall land-cover change. The results confirm major losses in scattered trees, mainly due to urbanization, agricultural intensification, and land abandonment. They further reveal that, while orchards have persisted in total area, they have undergone critical changes towards a simplified landscape structure and loss of the traditional land-use mosaic, which is a characterizing feature of high nature value landscapes. Multi-temporal assessment showed that most trends have been continuous and did not change directions over time, but rather accelerated during periods of rapid change (most dramatically in the 1950-1990 period). The case of orchards and scattered trees illustrates a major problem of cultural landscapes in Europe: Semi-natural landscape features of high nature value are threatened by both intensification and abandonment of land uses. This makes their conservation a potentially costly enterprise, as both opportunity costs for lost alternative land uses and for conservation management costs arise.
Agroecosystems are vital for supplying ecosystem services to human society, but most modern farming practices impact detrimentally on the environment. Public agricultural support policies have been critically important in influencing the transformation of the farm sectors; however, few of them have been dedicated to enhancing ecosystem services beyond agricultural commodities. The largest agricultural support system worldwide, the European Common Agricultural Policy (CAP), has now come to a critical point, as major decisions concerning its design and implementation after 2013 are about to be taken. The debate on this reform process presents a unique opportunity to trigger a transition from commodity-based subsidy policies to policies centered on efficient provision of ecosystem services from agricultural land. To prompt such discussion, we formulate key recommendations informed by a review of ecosystem services literature and address verifiable links to human well-being, non-market valuation for balanced services provision, treatment of ecosystem services bundles, site-specific and regionalized approaches, matching spatial scales for different ecosystem services, funding permanence for payment schemes, strong monitoring and adaptive approaches to tackling uncertainties, and coherent cross-sectoral policy design. If these issues were to be considered in formulating and implementing future CAP, it might become an exemplar for redirecting agricultural policies elsewhere in the world towards sustainability.
Most industrial countries have experienced a transformation of land use: from decreasing to expanding forest areas, the so-called forest transition. Outside closed forests, European rural landscapes exhibit a diversity of tree-based agricultural systems, but the question of whether this forest transition has also affected ‘trees outside forests’ has rarely been studied. The aim of this study is to analyze the spatial-temporal dynamics of farm trees and woodlands in an agricultural landscape in Eastern Germany from 1964 to 2008, based on aerial photographs and digital orthophotos. Taking a landscape ecological perspective, we quantify farm tree dynamics, disentangle processes of gain and loss in the socialist and post-socialist periods of Eastern Germany, and assess differences in ecosystem services provided by farm trees. A substantial increase of overall tree cover by 24.8% was observed for the selected time period, but trajectories have been disparate across different farm tree classes. The increase in tree cover was stronger in steep valleys than on hills and plateaus, indicating a significant interdependence between topography and trajectories of change. Patch numbers of farm trees did not increase, which suggests that the expansion of tree cover is mostly due to a spatial expansion of previously existing tree patches. Overall net gains in tree cover were rather similar during the socialist and post-socialist eras. The general increase in tree cover was accompanied by increases in agriculture-related ecosystem service provision, but the increase in pollination and pest control services was much lower than that in water purification services. These findings present the first empirical evidence from an industrialized country that there is also an ongoing ‘forest transition’ outside closed forests. Potential, partially counteracting drivers of change during the socialist and post-socialist periods have mainly been related to farm policies and the environmental consciousness of land users and society as a whole.