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Single-cell analyses comprise a multitude of analytical methods that share a common feature, namely the focus on individual cells. This is in contrast to previous methods that provided summarized data for cell clusters, groups of cells, tissues and organs. The new field offers huge potential not only for basic research, but also for medical and biotechnological applications, as it opens up new levels in the context-related and personal interpretation of biological interconnections. This brochure on single-cell analysis provides an overview on the new possibilities from the viewpoint of developmental biology, biomedicine and bioinformatics, but also addresses possible social im-plications and consequences.
Socioeconomic inequalities are functions not only of intrinsic differences between persons or groups, but also of the dynamics of their interactions. Inequalities can arise and become stabilized if there are advantages (such as generalized wealth including “human capital”) which are self-enhancing, whereas depletion of limiting resources is widely distributed. A recent theory of biological pattern formation has been generalized, adapted and applied to deal with this process. Applications include models for the non-Gaussian distribution of personal income and wealth, for overall economic growth in relation to inequalities and for effects of uncoupling strategies between developing and developed countries. Note added after publication: The equations (14) for the model of the income distribution, with its characteristic non-Gaussian extension towards higher incomes (fig.4), are closely related to the Fokker-Planck equation that is widely applied in many fields of physics.
Some drawings from the >Paper Museum< of Cassiano dal Pozzo and the Berlin Codex Destailleur >D<
(2004)
With the present report the Berlin-Brandenburg Academy of Sciences and Humanities wants to draw attention to the results of one of its interdisciplinary projects, which are published elsewhere in more detail. The authors believe that their particular approach to the subject of "waste energy recovery", in combination with an interdisciplinary perspective, suggests a new way of discussing energy problems that has the potential to lead to qualified statements...
Within the sedimentation diagram of infective RNA preparations isolated from Tobacco Mosaic Virus, undegraded molecules form a sharp peak with a molecular weight corresponding to the total RNA content of the virus particle. Degradation kinetics by ribonuclease is of the linear, single-target type, indicating that the RNA is single-stranded. The intact RNA of a virus particle thus forms one big single-stranded molecule. Quantitative evaluation of the effect degradation by RNA-ase on the infectivity of the RNA shows that the integrity of the entire molecule is required for its biological activity.
Current financial and monetary difficulties in Europe are overshadowing the issue of a lack of common European identity. 200 years of nation states seem to have suppressed 1800 years of a history shaped by mutual enrichment in politics, science and the arts – a European cultural heritage. It is for the humanities and social sciences (SSH) to research, document and preserve this heritage, where the European science academies play a major role. However, a pan-European research programme on European cultural heritage and identity is still lacking, and, in comparison to the rest of the European SSH research landscape, the science academies are terra incognita. This book provides an analytical report of the first survey of basic research in the SSH conducted by the European scientific academies and related research organisations. It not only provides greatly needed information about this important area of the European research landscape, but also investigates the potential for a pan-European academies’ research programme in the SSH (including a corresponding digital infrastructure) that could strengthen the integration of European research into cultural heritage and identity. The main topic of this publication is the working practices of the projects surveyed with a focus on: o the science academies of Europe o research fields and topics o running times and funding o staff and early-stage researchers o research sites and access to research material o digital research practices o publication, dissemination and visibility o international collaboration o project evaluation
The concept of ecosystem services was developed capitalizing on ecological knowledge that ecosystems perform various functions like increasing or retarding water fluxes, cleansing or polluting water, modifying microclimatic conditions, sustaining or impoverishing biological diversity and so on. There is growing body of ecological knowledge that management of agricultural landscape for its structural diversity is becoming the important pillar of the sustainability of rural areas. Programmes of environmental protection in rural areas should aim not only at introduction environmental friendly technologies of cultivation within farm. They should also be concerned with challenge of how to increase the resistance or resilience of the whole landscape against threats. Recognition of non -commodity effects of diversified agricultural landscape formed by introduction into cultivated fields shelterbelts, stretches of meadows, small mid -field water reservoirs and other biogeochemical barriers provide new options to combine societal demands with environment production. Co -adaptation of human activities with landscape services relies on policy that economic processes should be conformed with ecological processes operating in the region which are enhancing landscape capacities for naturalization of pollution, regeneration of wastes, recycling of water recourses as well as increasing resistance or resilience of the whole system to stresses caused by production of goals required by society. Recognition of system multifunctionality helps to achieve that goal. The knowledge on processes underpinning ecosystem services opened new frontiers for management of landscapes' structures towards enhancing their capacities to deliver requested services. Forests and shelterbelts show similar functions in the landscape but network of shelterbelts perform many similar services like forests growing on smaller part of landscape area. According to studies carried out by Research Centre for Agricultural and Forest Environment in Poland the following functions of shelterbelts are similar to those shown by forests when 4 -5% of the landscape area is under the network of shelterbelts: - modify the microclimatic conditions and heat and water balances; - control the water chemistry composition (control of diffuse pollution); - limit water and wind erosion; - protect the biodiversity; - increase the survival of the game animals; - enhance recreational value of the region; - provide wood and other products; - promote aesthetic values of the countryside. In this review the first four functions of agricultural landscape within Turew neighborhood will be presented.