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Applying mild methods of preparation, part of the ribosomes of rabbit reticulocytes are found in aggregates (later called polyribosomes) of up to six ribosomal units. Upon treatment with RNA-ase, they desintegrate into single ribosomes. The fast-sedimenting aggregates are found to be more active in protein synthesis in terms of incorporation of radioactive amino acids, whereas the single ribosomes are more receptive to stimulation by the artificial messenger RNA poly-U. The findings indicate that the linkage of ribosomes into aggregates is due to the messenger RNA. They support a tape-reading mechanism of protein synthesis whereby growth of the peptide chain is accompanied by shifting the active site of the ribosome from one coding group of nucleotides of the messenger RNA to the next.
Full applicability of physics to human biology does not necessarily imply that one can uncover a comprehensive, algorithmic correlation between physical brain states and corresponding mental states. The argument takes into account that information processing is finite in principle in a finite world. Presumbly the brain-mind-relation cannot be resolved in all essential aspects, particularly when high degrees of abstraction or self-analytical processes are involved. Our conjecture plausibly unifies the universal validity of physics and a logical limitation of human thought, and it does not regard consciousness -the most basic human experience - as a marginal phenomenon. ++++ RATIO appeared up to 1987 in both a German and an English version. The German title of this article: Alfred Gierer, Der physikalische Grundlegungsversuch in der Biologie und das psychophysische Problem. RATIO XII, Heft 1, 1970, S. 40-54.
Socioeconomic inequalities are functions not only of intrinsic differences between persons or groups, but also of the dynamics of their interactions. Inequalities can arise and become stabilized if there are advantages (such as generalized wealth including “human capital”) which are self-enhancing, whereas depletion of limiting resources is widely distributed. A recent theory of biological pattern formation has been generalized, adapted and applied to deal with this process. Applications include models for the non-Gaussian distribution of personal income and wealth, for overall economic growth in relation to inequalities and for effects of uncoupling strategies between developing and developed countries. Note added after publication: The equations (14) for the model of the income distribution, with its characteristic non-Gaussian extension towards higher incomes (fig.4), are closely related to the Fokker-Planck equation that is widely applied in many fields of physics.
The short paper introduces the concept of possible branches of double-stranded DNA (later sometimes called palindromes): Certain sequences of nucleotides may be followed, after a short unpaired stretch, by a complementary sequence in reversed order, such that each DNA strand can fold back on itself, and the DNA assumes a cruciform or tree-like structure. This is postulated to interact with regulatory proteins.
We expose analogies between turbulence in a fluid heated from below (Rayleigh-Bénard (RB) flow) and shear flows: The unifying theory for RB flow (S.Grossmann and D.Lohse, J.Fluid Mech. 407, 27-56 (2000) and subsequent refinements) can be extended to the flow between rotating cylinders (Taylor-Couette flow) and pipe flow. We identify wind dissipation rates and momentum fluxes that are analogous to the dissipation rate and heat flux in RB flow. The proposed unifying description for the three cases is consistent with the experimental data.
Alexander von Humboldt’s maps, graphs and illustrations contain a great deal of detail, but in the available rare editions they are hardly visible to the naked eye. In many editions they have been reduced. In a digital library, they will become accessible in their entirety, and Internet technology will reproduce them in a form that overcomes the limitations of the original printing. The user will be able to enlarge the images and see details that might have been overlooked in the past. The Humboldt’s digital library will adhere to the standards for digital libraries established by the Open Archives Initiative (OAI) and the tools EPRINTS and DSPACE to provide the Web services and determine the most effective way to establish dynamic linking and knowledge based searching of information within the archive.
Alexander von Humboldt’s descriptions of volcanic mountains in his travel journals (Reise auf dem Río Magdalena, durch die Anden und Mexico) show both his reliance on and impatience with literary conventions and travel narratives. Using Goethe’s Italienische Reise and Bürger’s Münchhausen as points of comparison for literary treatments of the volcano ascent, Humboldt’s process of writing is examined. Humboldt shows the failure of the existing discourse and begins to experiment with narratives which fragment and recombine personal and historical modes of writing with, in this case, images from new technical inventions which visualize landscape according to fundamental scientific principles. While the inclusion of scientific prose is relevant, Humboldt’s link to modernity is based on experimental narrative techniques which draw upon changing sets of discourse practices to describe complex realities.
Some drawings from the >Paper Museum< of Cassiano dal Pozzo and the Berlin Codex Destailleur >D<
(2004)
Responding to the Antique : a rediscovered Roman Circus Sarcophagus and its Renaissance Afterlife
(2005)
Stephen Jay Gould wrote recently that “when Church began to paint his great canvases, Alexander von Humboldt may well have been the world’s most famous and influential intellectual.” Humboldt’s influence in the case of the landscape artist Church is especially interesting. If we examine the precise relationship between the German explorer and his American admirer, we gain an insight into how Humboldt transformed Church’s life and signaled a new phase in the career of the artist. Church retraced Humboldt’s travels in Ecuador and in Mexico. If we compare the texts available to Church and the comparison of Church’s paintings and the texts and images of Humboldt’s works we can arrive at new perspectives on Humboldt’s extraordinary influence on American landscape painting in the nineteenth century.
Mind, Matter and Mathematics
(2008)
Non-Oberbeck-Boussinesq (NOB) effects on the Nusselt number Nu and Reynolds number Re in strongly turbulent Rayleigh-Benard convection in liquids were investigated both experimentally and theoretically. In the experiment, the heat current, the temperature difference, and the temperature at the horizontal mid-plane were measured. Three cells of different heights L, all filled with water and all with aspect ratio T close to 1 were used. For each L, about 1.5 decades in Ra were covered, together spanning the ränge 108 < Ra < 1011. For the largest temperature difference between the bottom and top plates of ? = 40K the kinematic viscosity and the thermal expansion coefficient, due to their temperature dependence, varied by more than a factor of two. The Oberbeck-Boussinesq (OB) approximation of temperature independent material parameters thus was no longer valid. The ratio Ï? of the temperature drops across the bottom and top thermal boundary layers became as small as Ï? = 0.83, as compared to the ratio Ï? = 1 in the OB case. Nevertheless, the Nusselt number Nu was found to be only slightly smaller (at most 1.4%) than in the next larger cell with the same Rayleigh number, where the material parameters were still nearly height-independent. The Reynolds numbers in the OB and NOB case agreed with each other within the experimental resolution of about 2%, showing that NOB effects for this parameter were small as well. Thus Nu and Re are rather insensitive against even significant deviations from OB conditions. Theoretically, we first account for the robustness of Nu with respect to NOB corrections: the NOB effects in the top boundary layer cancel those which arise in the bottom boundary layer as long as they are linear in the temperature difference ?. The net effects on Nu are proportional to ?2 and thus increase only slowly and still remain minor despite drastic material parameter changes. We then extend the Prandtl-Blasius boundary-layer theory to NOB Rayleigh-Benard flow with temperature dependent viscosity and thermal diffusivity. This allows the calculation of the shift of the bulk temperature, the temperature drops across the boundary layers, and the ratio Ï? without introducing any fitting parameter. The calculated quantities are in very good agreement with experiment. When in addition we use the experimental finding that for water the sum of the top and bottom thermal boundary-layer widths (based on the slopes of the temperature profiles at the plates) remains unchanged under NOB effects within experimental resolution, the theory also gives the measured small Nusseltnumber reduction for the NOB case. In addition, it predicts an increase by about 0.5% of the Reynolds number, which is also consistent with the experimental data. By theoretically studying hypothetical liquids with only one of the material parameters being temperature dependent, we shed further light on the origin of NOB corrections in water: While the NOB deviation of x from its OB value Ï? = 1 mainly originates from the temperature dependence of the viscosity, the NOB correction of the Nusselt number primarily originates from the temperature dependence of the thermal diffusivity. Finally, we give the predictions from our theory for the NOB corrections if glycerol is used as operating liquid.