Refine
Year of publication
- 2024 (1)
- 2023 (1)
- 2021 (3)
- 2019 (14)
- 2018 (6)
- 2016 (2)
- 2015 (8)
- 2014 (4)
- 2013 (11)
- 2012 (12)
- 2011 (14)
- 2010 (3)
- 2009 (5)
- 2008 (3)
- 2007 (5)
- 2006 (14)
- 2005 (11)
- 2004 (5)
- 2003 (4)
- 2002 (7)
- 2001 (13)
- 2000 (8)
- 1999 (7)
- 1998 (3)
- 1997 (1)
- 1993 (1)
- 1988 (1)
- 1987 (1)
- 1983 (1)
- 1981 (1)
- 1972 (2)
- 1970 (1)
- 1966 (1)
- 1963 (1)
- 1958 (1)
- 1957 (1)
- 1956 (1)
Document Type
- Part of a Book (61)
- Article (59)
- Working Paper (16)
- Conference Proceeding (12)
- Preprint (12)
- Lecture (10)
- Book (3)
- Report (3)
- Other (2)
Language
- English (178) (remove)
Keywords
- Ökosystem (15)
- Antike (12)
- Klimaänderung (12)
- Region Berlin-Brandenburg (10)
- Wasserhaushalt (10)
- Biowissenschaften (8)
- Korpus <Linguistik> (8)
- Kunstgeschichte (8)
- Denkmalpflege (7)
- Historische Gärten (7)
Has Fulltext
- yes (178)
Institute
- Berlin-Brandenburgische Akademie der Wissenschaften (45)
- Veröffentlichungen von Akademiemitgliedern (25)
- Akademienvorhaben Census of Antique Works of Art and Architecture Known in the Renaissance (14)
- Interdisziplinäre Arbeitsgruppe Globaler Wandel (13)
- Interdisziplinäre Arbeitsgruppe Gegenworte - Hefte für den Disput über Wissen (8)
- Akademienvorhaben Alexander-von-Humboldt-Forschung (7)
- Drittmittelprojekt Ökosystemleistungen (7)
- Interdisziplinäre Arbeitsgruppe Historische Gärten im Klimawandel (7)
- Akademienvorhaben Deutsches Wörterbuch von Jacob Grimm und Wilhelm Grimm (6)
- Akademienvorhaben Strukturen und Transformationen des Wortschatzes der ägyptischen Sprache. Text- und Wissenskultur im alten Ägypten (6)
Since humans are preferentially settling in flood plains they often influence freshwater systems intensely. The first signs of anthropogenic impacts on surface waters in the Berlin-Brandenburg region are approximately 3000 years old. Considering the multiple and intense human uses of surface waters in this region, we analysed when, how and to which extent regional rivers and streams became impacted by dams, water mills and fish weirs resulting in changes in morphology, hydrology and ecological functioning. We hypothesise that the development and growth of cities in this region necessitated (1) efficient navigability of rivers linking them, (2) efficient use of hydropower resources for mills, and (3) significant pollution of surface waters especially with the beginning of industrial development. We analyse these hypotheses by means of three regional examples and delineate the effects of human uses on selected surface water bodies. Understanding the effects of these historic modifications of surface water supports the identification of options for a sustainable use of surface waters that are currently still subjected to multiple uses but face a significant decrease in discharge due to climate change.
Early-career funding in German-African academic cooperation: achievements, challenges, perspectives
(2024)
This paper analyses experiences, challenges and potentials in German-African academic cooperation in the field of early-career funding considering the humanities and social sciences as well as natural sciences and medicine. It is based on a comprehensive overview of existing German funding formats and an exemplary survey of the experiences of African cooperation partners with these programmes. The authors propose the establishment of an interface between academic research, the practice of science funding, and African researchers. According to the authors, such a contact and information point would contribute to the improvement of German-African science cooperation and be an important element of Germany’s scientific diplomacy in the long term. This paper is the English translation of Denkanstoß 13 (2023): Early-Career-Förderung in der deutsch-afrikanischen Wissenschaftskooperation. Leistungen, Herausforderungen, Perspektiven. Berlin.
For decades, water resources have been used intensively for drinking water, industry, agriculture and energy production. This paper summarises the main anthropogenic influences on the water cycle in a Pleistocene landscape and associated geochemical reactions. The results allow the identification and description of the main hydraulic and geochemical processes that control water and solute fluxes in different hydrological compartments, in particular recharge and discharge regions. Under progressive climate change, this process-based knowledge should be used to adapt land and water management to minimise negative impacts on hydrological resources and stabilise the regional water balance in theBerlin-Brandenburg Pleistocene landscape. Based on these results, a risk assessment approach for validation of future management strategies under changing climate conditions is presented.
The future of biological diversity in a crowded world (Ernst Mayr Lecture on 29th October 2002)
(2006)
The Swedish Academy Dictionary (SAOB) is one of the big national dictionary projects started in the 19th century. SAOB is still in production – there are another two volumes out of 38 to printed before 2018. The structure inside the volumes is (of course) varied/varying. There are ten chief editors and five generations of editors involved in the project. In the 1980s the SAOB was OCR-scanned. The result was used for a webversion in the internet from 1997. The webversion is very frequently used but has a lot of shortcomings due to, among other things, a great typographic complexity and a scanning technology of the time. Now the editorial board is discussing the future: redigitalization (in China), updating of the webversion with new search tools, updating of the dictionary itself and some form of editing tool.
A reaction to the article „The Lost Archive“, The Wall Street Journal 12.1.2008, page 1 (US edition) http://online.wsj.com/article/SB120008793352784631.html The belief in the myth that old manuscripts should be mysterious and powerful is part and parcel of the age of Modernity. That such expectations were operative in the discussion on the Qumran fragments is still remembered, and more recently the Da Vinci Code, in itself a quite shallow story, sold extremely well. The fact that the Wall Street Journal placed an article on the “lost Bergsträsser-film archive” of Qur’anic manuscripts on its front page on 12th of January seems to be due to the myth of “textual wars” taking place in the world.
Emergence, analysis and optimization of structures - Concepts and strategies across disciplines
(2007)
The study of structures is a common concern of all scientific disciplines. The motivation as well as the methods of analysis, however, differ considerably. In engineering, the generation of artifacts, of infrastructures or technological processes are of primary interest. Frequently, the analysis aims at an optimization of the structures and the structure generating processes. Quite different is the study and explanation of existing structures in biology and the social sciences. Here the question of optimality does not present itself in an unambiguous manner. Generally, it must be questioned whether biological and social structures, although developing in an evolutionary way, can be considered as leading towards an a-priori defineable goal of optimality. The complex scenario of qualitative and quantitative modeling, and the goal-oriented and statistical approaches to understanding the meliorisation efforts in the various fields of the sciences and humanities define the scope of this book. Its intention is to create trans-disciplinary insights into methods to fecundate the custom disciplinary approaches.
Climate change is expected to increase water scarcity in northeast Germany. Land-use change is one of the options of mitigation that is intensely discussed in this region. This review aims at giving a compilation of existing data and modelling studies in order to investigate the potential and the limits of the land-use change approach.
My essay attends to a number of passages in Alexander von Humboldt’s "Personal Narrative" in which the Prussian explorer expresses anxiety about the apparent dangers posed by the overwhelmingly productive tropical landscapes he observes. In these passages, the excesses of an “exotic nature” threaten European identity and modes of civilization—and they trouble the accuracy of Humboldt’s own observational project. I also explore Humboldt’s related worry that South American vegetable (and visual) overload will exert a destabilizing effect on his aesthetic sensibility, disrupting his ability to represent the “New Continent” accurately in writing. Finally, I sketch the influence of Humboldt’s representations of tropical excess on nineteenth-century British cultural thought and literary practice. Studying the instabilities experienced by "Personal Narrative’s" expatriates and colonists promises to draw out important tensions latent in Humboldt’s treatment of tropical landscape and to illuminate broader epistemological and aesthetic shifts being worked out during the period.
Current financial and monetary difficulties in Europe are overshadowing the issue of a lack of common European identity. 200 years of nation states seem to have suppressed 1800 years of a history shaped by mutual enrichment in politics, science and the arts – a European cultural heritage. It is for the humanities and social sciences (SSH) to research, document and preserve this heritage, where the European science academies play a major role. However, a pan-European research programme on European cultural heritage and identity is still lacking, and, in comparison to the rest of the European SSH research landscape, the science academies are terra incognita. This book provides an analytical report of the first survey of basic research in the SSH conducted by the European scientific academies and related research organisations. It not only provides greatly needed information about this important area of the European research landscape, but also investigates the potential for a pan-European academies’ research programme in the SSH (including a corresponding digital infrastructure) that could strengthen the integration of European research into cultural heritage and identity. The main topic of this publication is the working practices of the projects surveyed with a focus on: o the science academies of Europe o research fields and topics o running times and funding o staff and early-stage researchers o research sites and access to research material o digital research practices o publication, dissemination and visibility o international collaboration o project evaluation
Berlin Text System 3.1 User Manual : Editorial Software of the Thesaurus Linguae Aegyptiae Project
(2018)
The Berlin Text System (BTS) Version 3.1 manual introduces a Java-based software designed for editing and annotating Ancient Egyptian texts. BTS integrates a CouchDB database and an Elastic search engine to support its main components: Text Editor, Lemma List, Thesaurus, and Abstract Text.
The Text Editor facilitates transliteration, translation, lemmatization, and annotations, allowing for detailed lexical and grammatical analysis. Hieroglyphic transcriptions can be entered via a specialized Hieroglyph Type Writer based on JSesh.
The Lemma List ist ready to contain pre-Coptic lemmata, divided into Hieroglyphic/Hieratic and Demotic scripts, providing comprehensive entries with passport data, transliterations, and translations.
The Thesaurus allows for metadata enrichment of texts with controlled vocabulary for consistent data management, supporting contextual analysis through structured metadata.
The manual covers BTS's user interface, including menu bar, toolbar, status bar, and workspace, divided into views for each main component. Features like Revision History for tracking and restoring versions, indexing, and search capabilities enhance user efficiency. BTS is a powerful tool for the study and preservation of Ancient Egyptian texts, integrating advanced database and search technologies with specialized textual analysis tools.
Even a reductionist attempt to define scholarship is clearly fraught with difficulty, but an idealised historical lexicographer-cum-scholar must obviously have – inter alia and at the very least – a profound linguistic and textual knowledge of the language being documented, an ability to understand texts in their historical context and to analyse the meaning or function of lexical items as used in context, an ability to synthesise the results through generalisation and abstraction and to formulate them in a way that is both accurate, i.e. reflects actual usage, and user- or reader-friendly, i.e. is comprehensible to the user/reader. S/he must have encyclopedic or world knowledge and literary skills in order to understand general content words and explain their meaning and their semantic shifts perhaps over many centuries, and technical expertise to understand specialist terms and define their use in specific contexts, again perhaps over time. In respect of etymology s/he must not only have knowledge of older stages of the language and an ability to reconstruct unattested forms, but also knowledge of the other languages that have impacted on the language being documented, or at least familiarity with the scholarly historical dictionaries of those languages. That is a tall order indeed, impossibly tall for any one person today given today‘s demands on and expectations of lexicographers. Teams which include specialists in different areas or at least have access to consultants in such areas alongside generalists are needed if scholarly standards are to be met. The standard of scholarship is primarily a factor of the number and range as well as the knowledge and experience of the lexicographers, as is in large measure the pace of production. In this regard, it cannot be emphasised enough that scholarly historical lexicography of high quality is and will remain very time consuming.
Even a reductionist attempt to define scholarship is clearly fraught with difficulty, but an idealised historical lexicographer-cum-scholar must obviously have – inter alia and at the very least – a profound linguistic and textual knowledge of the language being documented, an ability to understand texts in their historical context and to analyse the meaning or function of lexical items as used in context, an ability to synthesise the results through generalisation and abstraction and to formulate them in a way that is both accurate, i.e. reflects actual usage, and user- or reader-friendly, i.e. is comprehensible to the user/reader. S/he must have encyclopedic or world knowledge and literary skills in order to understand general content words and explain their meaning and their semantic shifts perhaps over many centuries, and technical expertise to understand specialist terms and define their use in specific contexts, again perhaps over time. In respect of etymology s/he must not only have knowledge of older stages of the language and an ability to reconstruct unattested forms, but also knowledge of the other languages that have impacted on the language being documented, or at least familiarity with the scholarly historical dictionaries of those languages. That is a tall order indeed, impossibly tall for any one person today given today‘s demands on and expectations of lexicographers. Teams which include specialists in different areas or at least have access to consultants in such areas alongside generalists are needed if scholarly standards are to be met. The standard of scholarship is primarily a factor of the number and range as well as the knowledge and experience of the lexicographers, as is in large measure the pace of production. In this regard, it cannot be emphasised enough that scholarly historical lexicography of high quality is and will remain very time consuming.
Die Erscheinungsform einer bestimmten Einzelsprache resultiert aus dem Nebeneinander und Zusammenwirken vertikaler und horizontaler Transmission von sprachlichen Merkmalen und umfasst demzufolge normalerweise neben Phänomenen, die über eine Kette früherer Sprechergenerationen ererbt wurden, auch solche, die aus anderen Sprachen entlehnt wurden. Deutliche Spuren einer komplexen Entstehungsgeschichte und der Interaktion verschiedener Sprachgemeinschaften lassen sich nicht erst im Altägyptischen oder gar erst in der Sprache des Neuen Reiches ausmachen, sondern bereits die frühesten schriftlichen Quellen aus der Zeit um 3000 v. Chr. erlauben – trotz ihrer Knappheit – überraschende Einblicke in die zeitgenössischen sprachlichen Verhältnisse. Bislang nur durch Sprachvergleich rekonstruierbare Entwicklungen sind nunmehr historisch nachweisbar, und das phonologische System einer dem Altägyptischen vorausgehenden und erheblich von ihm abweichenden Sprachstufe wird greifbar. Da das Voraltägyptische ein für eine afroasiatische Sprache eher untypisches Konsonanteninventar besitzt und sich zudem lexikalische Übereinstimmungen (nicht-genetischer Natur) mit indoeuropäischen Sprachen abzeichnen, erscheinen fundierte Hypothesen über die Herausbildung des Ägyptischen nicht länger unmöglich. Damit wäre das Ägyptische nicht nur die am längsten bezeugte Einzelsprache der Menschheitsgeschichte, sondern wohl auch die einzige, die von ihrer Entstehung bis zu ihrem Aussterben schriftlich dokumentiert ist.
Virtually all conventional text-based natural language processing techniques - from traditional information retrieval systems to full-fledged parsers - require reference to a fixed lexicon accessed by surface form, typically trained from or constructed for synchronic input text adhering strictly to contemporary orthographic conventions. Unconventional input such as historical text which violates these conventions therefore presents difficulties for any such system due to lexical variants present in the input but missing from the application lexicon. To facilitate the extension of synchronically-oriented natural language processing techniques to historical text while minimizing the need for specialized lexical resources, one may first attempt an automatic canonicalization of the input text. This paper provides an informal overview of the various canonicalization techniques currently employed by the Deutsches Textarchiv project at the Berlin-Brandenburg Academy of Sciences and Humanities to prepare a corpus of historical German text for part-of-speech tagging, lemmatization, and integration into a robust online information retrieval system.
Introduction
(2019)
Global change is posing a major challenge to existing forms of natural resource use, socio-economic development and institutional regulation. Although trends such as climate change, socio-economic transformation and institutional change are global in their scope, they have very specific regional outcomes. Regionally distinct coping strategies are required which take into account both the diversity of regional impacts of global change and the local contexts of appropriate responses. This paper explores the impacts of global change on the management of water infrastructure systems in the Berlin-Brandenburg region in terms of three concurrent and overlapping challenges: climate change, socio-economic change and institutional change. It subsequently examines how regional actors in the water sector are addressing these three dimensions of global change.
Over millennia human well-being has benefited from ecosystems, not only through tangible goods, but also through intangible assets known as cultural ecosystem services. Despite growing research over the last decade, cultural services assessment still remains arbitrary and is largely limited to marketable services such as tourism. Evident difficulties in standardizing definitions and measurements have challenged cultural services accounting in decision making processes. However, the imminent formation of the Intergovernmental Platform on Biodiversity and Ecosystem Services offers an opportunity to counterbalance this misrepresentation by establishing a scientific basis for consistently assessing cultural services. In that regard, the current review intends to facilitate discussion investigating the current state of cultural services accounting by offering an appraisal of existing evidence regarding cultural services indicator quality. The current review builds on scientifically recognized frameworks to develop a holistic understanding of how cultural services indicators are conceived within ecosystem services research. Among the measures found, benefit indicators were most frequently used for assessing inspirational, educational and recreational services. A broad variety of methods for accounting cultural services was found, mainly due to the varied aims of the studies. Most of the cultural services indicators were deficient concerning their clarity of definitions, purposes and understanding of the processes to be measured and referring only marginally to tradeoffs and bundles with other services. Only 17% performed multitemporal assessments and 23% used spatially explicit information. It seems that cultural services indicators quality could be greatly enhanced by investing more effort towards involving relevant stakeholders in conceptualization and communication phases, using participatory mapping tools to enhance visibility.
From exclusion to inclusion : improving clinical research in vulnerable populations ; memorandum
(2014)
Therapeutic care for vulnerable populations – meaning patient groups such as underage children and the mentally ill that have limited or no capacity for giving informed consent – is severely lacking. Thus, for example, a great portion of pharmaceuticals used in the treatment of children and youth have not been specifically designed for these groups, which often results in side effects that are disproportionate to those associated with such medicines when used by adults. Moreover, vulnerable populations are at times faced with having no therapies at all for some of their ailments, such that children and dementia sufferers, for example, are often considered to be “therapeutic orphans”. It is therefore urgent that clinical research be carried out among vulnerable populations in order to improve their therapeutic possibilities. The Clinical Research on Vulnerable Populations Research Group – a cooperative effort between the Berlin-Brandenburg Academy of Sciences and Humanities (Berlin, Germany) and the European Academy of Technology Assessment (Bad Neuenahr, Germany) – has set itself the task of analyzing the state of clinical research on vulnerable populations so as to be able to develop suggestions for improving future research of this kind. The results of this work are presented in the following memorandum, which seeks to portray the state-of-the-art in this domain while also assessing the strengths and weaknesses of contemporary ethical and medical perspectives related to it. The memorandum is primarily oriented towards those in the relevant scientific disciplines who can benefit from obtaining an informed consensus regarding the current state of the discussions taking place around this topic.
Among mass digitization methods, double-keying is considered to be the one with the lowest error rate. This method requires two independent transcriptions of a text by two different operators. It is particularly well suited to historical texts, which often exhibit deficiencies like poor master copies or other difficulties such as spelling variation or complex text structures. Providers of data entry services using the double-keying method generally advertise very high accuracy rates (around 99.95% to 99.98%). These advertised percentages are generally estimated on the basis of small samples, and little if anything is said about either the actual amount of text or the text genres which have been proofread, about error types, proofreaders, etc. In order to obtain significant data on this problem it is necessary to analyze a large amount of text representing a balanced sample of different text types, to distinguish the structural XML/TEI level from the typographical level, and to differentiate between various types of errors which may originate from different sources and may not be equally severe. This paper presents an extensive and complex approach to the analysis and correction of double-keying errors which has been applied by the DFG-funded project “Deutsches Textarchiv” (German Text Archive, hereafter DTA) in order to evaluate and preferably to increase the transcription and annotation accuracy of double-keyed DTA texts. Statistical analyses of the results gained from proofreading a large quantity of text are presented, which verify the common accuracy rates for the double-keying method.
The FEW is a huge dictionary when we consider the sheer mass of data (25 volumes, 16000 pages) and its exhaustive aims. It has indeed the purpose of registering and etymologizing the whole lexicon, not only of French, but also of earlier stages of the language and of Occitan; of every Gallo-romance dialect; of every technical or professional genre; of every language register, including slang. Summing up, the FEW aims to include and describe every single lexical unit which exists or has existed in the territory of ancient Gaul. The sheer size of this undertaking means two things, which directly influence the digitalisation of the dictionary: Firstly, there is a a huge amount of data; secondly, the presentation and organization of the data is exceedingly complex. The reasons for digitalising the FEW are the easy searches for units, and the carrying out of searches using criteria that are not possible to use with the printed version. However, the fulfillment of these purposes includes some risks, and potentially the cutting of some corners, especially the temptation of renouncing reading.
An der Sprache des Rechts wird Kritik geübt, seit die Aufklärung die Verständlichkeit der Gesetze zu ihrem Anliegen gemacht hat. Mit den großen Kodifikationen des Rechts im ausgehenden 19. Jahrhundert hat die Kritik am angeblich schlechten, unverständlichen Juristendeutsch eine besondere demokratietheoretische Legitimation bekommen. Diese Sprachkritik sucht seit den siebziger Jahren vermehrt bei der Linguistik Rat, wie denn eine bessere Allgemeinverständlichkeit von Rechtstexten verwirklicht werden könnte. Der Band versammelt systematisch aufeinander bezogene Beiträge ausgewiesener Linguisten, Juristen und Schriftsteller zur Problematik des Verständnisses juristischer Sprache, zur Methodik empirischer Verständlichkeitsmessung und zu den Möglichkeiten transdisziplinärer Kooperation zwischen Rechts- und Sprachwissenschaftlern.
The article summarizes the contents and the structurtal premises of the “Thesaurus Indogermanischer Text- und Sprachmaterialien” (TITUS), focussing on search functions and facilities and questions of the encoding of ancient languages written in various scripts. Examples are taken from Tocharian, Greek, Vedic Sanskrit, and other ancient Indo-European languages covered by TITUS.
Upon separation of the protein from the nucleic acid component of tobacco mosaic virus by phenol, using a fast and gentle procedure, the nucleic acid is infective in assays on tobacco leaves. A series of qualitative and quantitative control experiments demonstrates that the biological activity cannot depend on residual proteins in the preparation, but is a property of isolated nucleic acid which is thus the genetic material of the virus.
The generation of viral mutants in vitro was demonstrated by treatment of the isolated RNA of Tobacco Mosaic Virus by nitrous acid. This agent causes deaminations converting cytosine into uracil, and adenine into hypoxanthine. Our assay for mutagenesis was the production of local lesions on a tobacco variety on which the untreated strain produces systemic infections only. A variety of different mutants are generated in this way. Quantitative analysis of the kinetics of mutagenesis leads to the conclusion that alteration of a single out of the 6000 nucleotides of the viral RNA is sufficient for causing a mutation.
The paper addresses the formation of striking patterns within originally near-homogenous tissue, the process prototypical for embryology, and represented in particularly puristic form by cut sections of hydra regenerating a complete animal with head and foot. Essential requirements are autocatalytic, self-enhancing activation, combined with inhibitory or depletion effects of wider range - “lateral inhibition”. Not only de-novo-pattern formation, but also well known, striking features of developmental regulation such as induction, inhibition, and proportion regulation can be explained on this basis. The theory provides a mathematical recipe for the construction of molecular models with criteria for the necessary non-linear interactions. It has since been widely applied to different developmental processes.
Aggregates of previously isolated cells of Hydra are capable, under suitable solvant conditions, of regeneration forming complete animals. In a first stage, ecto- and endodermal cells sort out, producing the bilayered hollow structure characteristic of Hydra tissue; thereafter, heads are formed (even if the original cell preparation contained no head cells), eventually leading to the separation of normal animals with head, body column and foot. Hydra appears to be the highest type of organism that allows for regeneration of the entire structure from random cell aggregates. The system is particularly useful for studying cell interactions, tissue polarity, pattern formation, and cell differentiation.
Physical principles underlying biological pattern formation are discussed. In particular, the combination of local self-enhancement and long-range (“lateral”) inhibition (Gierer and Meinhardt, 1972) accounts for de-novo pattern formation, and for striking features of developmental regulation such as induction, spacing and proportion regulation of centers of activation in tissues and cells. Part I explains physical principles of spatial organisation in biological development. Part II demonstrates in mathematical terms that and how short-range activation and long-range inhibition are conditions for the generation of spatial concentration patterns. The conditions can be expressed in terms of ranges, rates and orders of reactions. These conditions, in turn, can also be derived by analysis of dynamic instabilities by means of Fourier waves, showing the neither obvious nor trivial relation between the latter approach and the theory based primarily on autocatalysis and lateral inhibition.
Validity of physical laws for any aspect of brain activity and strict correlation of mental to physical states of the brain do not imply, with logical necessity, that a complete algorithmic theory of the mind-body relation is possible. A limit of decodability may be imposed by the finite number of possible analytical operations which is rooted in the finiteness of the world. It is considered as a fundamental intrinsic limitation of the scientific approach comparable to quantum indeterminacy and the theorems of logical undecidability. An analysis of these limits, applied to dispositions of future behaviour, suggests that limits of decodability of the psycho-physic relation may actually exist with respect to brain states with self-referential aspects, as they are involved in mental processes. Limits for an algorithmic theory of the mind-body problem suggested by this study are formally similar to other intrinsic limits of the scientific method such as quantum indeterminacy and mathematical undecidability which are also related to self-referential operations. At the metatheoretical level, hard sciences, despite their reliability, universality and objectivity, depend on metatheoretical presuppositions which allow for multiple philosophical interpretations.
Aside from the increasing, impressive evidence on chemical identification of graded molecules involved, it is the capability of axons for approaching the target position from different aspects in a two-dimensional field which is per se a strong indication for the involvement of gradients. Targeting requires, in the target field, counter-graded effects, either by antagonistic gradients, or by a single gradient in each dimension exerting attractive effects at low, reverting to inhibitory (repulsive) effects at high concentrations. A further requirement for mapping is the modulation of the counter-graded effects by components of the growth cone itself which depends on the origin of the corresponding axon.Transduction and processing of graded signals in the navigating growth cones are proposed to be strongly enhanced by intra-growth-cone pattern formation. The concept also encompasses regulatory and branching processes including the formation of the terminal arbors.
Modern science, based on the laws of physics, claims validity for all events in space and time. However, it also reveals its own limitations, such as the indeterminacy of quantum physics, the limits of decidability, and, presumably, limits of decodability of the mind-brain relationship. At the philosophical level, these intrinsic limitations allow for different interpretations of the relation between human cognition and the natural order. In particular, modern science may be logically consistent with religious as well as agnostic views of humans and the universe. These points are exemplified through the transcript of a discussion between Kurt Gödel and Rudolf Carnap that took place in 1940. Gödel, discoverer of mathematical undecidability, took a proreligious view; Carnap, one of the founders of analytical philosophy, an antireligious view. By the time of the discussion, Carnap had liberalized his ideas on theoretical concepts of science: he believed that observational terms do not suffice for an exhaustive definition of theoretical concepts. Then, responded Gödel, one should formulate a theory or metatheory that is consistent with scientific rationality, yet also encompasses theology. Carnap considered such theories unproductive. The controversy remained unresolved, but its emphasis shifted from rationality to wisdom, not only in the Gödel-Carnap discussion but also in our time.
The development of modern science has depended strongly on specific features of the cultures involved; however, its results are widely and transculturally accepted and applied. The science and technology of electricity, for example, emerged as a specific product of post-Renaissance Europe, rooted in the Greek philosophical tradition that encourages explanations of nature in theoretical terms. It did not evolve in China presumably because such encouragement was missing. The transcultural acceptance of modern science and technology is postulated to be due, in part, to the common biological dispositions underlying human cognition, with generalizable capabilities of abstract, symbolic and strategic thought. These faculties of the human mind are main prerequisites for dynamic cultural development and differentiation. They appear to have evolved up to a stage of hunters and gatherers perhaps some 100 000 years ago. However, the extent of the correspondence between some constructions of the human mind and the order of nature, as revealed by science, is a late insight of the last two centuries. Unless we subscribe to extreme forms of constructivism or historical relativism, we may take the success and the formal structure of science as indications of a close, intrinsic relation between the physical and the mental, between the order of nature and the structure of human cognition. At the metatheoretical level, however, modern science is consistent with philosophical and cultural diversity.
The topic of this article is the relation between bottom-up and top-down, reductionist and “holistic” approaches to the solution of basic biological problems. While there is no doubt that the laws of physics apply to all events in space and time, including the domains of life, understanding biology depends not only on elucidating the role of the molecules involved, but, to an increasing extent, on systems theoretical approaches in diverse fields of the life sciences. Examples discussed in this article are the generation of spatial patterns in development by the interplay of autocatalysis and lateral inhibition; the evolution of integrating capabilities of the human brain, such as cognition-based empathy; and both neurobiological and epistemological aspects of scientific theories of consciousness and the mind.
Biological evolution and technological innovation, while differing in many respects, also share common features. In particular, the implementation of a new technology in the market is analogous to the spreading of a new genetic trait in a population. Technological innovation may occur either through the accumulation of quantitative changes, as in the development of the ocean clipper, or it may be initiated by a new combination of features or subsystems, as in the case of steamships. Other examples of the latter type are electric networks that combine the generation, distribution, and use of electricity, and containerized transportation that combines standardized containers, logistics, and ships. Biological evolution proceeds, phenotypically, in many small steps, but at the genetic level novel features may arise not only through the accumulation of many small, common mutational changes, but also when distinct, relatively rare genetic changes are followed by many further mutations. New evolutionary directions may be initiated by, in particular, some rare combinations of regulatory sections within the genome. The combinatorial type of mechanism may not be a logical prerequisite for biological innovation, but it can be efficient, especially when novel features arise out of already highly developed systems. Such is the case with the evolution of general, widely applicable capabilities of the human brain. Hypothetical examples include the evolution of strategic thought, which encompasses multiple self-representations, cognition-based empathy, meta-levels of abstraction, and symbolic language. These capabilities of biologically modern man may have been initiated, perhaps some 150 000 years ago, by one or few accidental but distinct combinations of modules and subroutines of gene regulation which are involved in the generation of the neural network in the cerebral cortex. This hypothesis concurs with current insights into the molecular biology of the combinatorial and hierarchical facets of gene regulation that underlie brain development. A theory of innovation encompassing technological as well as biological development cannot per se dictate alternative explanations of biological evolution, but it may help in adding weight and directing attention to notions outside the mainstream, such as the hypothesis that few distinct genetic changes were crucial for the evolution of modern man.
Within the sedimentation diagram of infective RNA preparations isolated from Tobacco Mosaic Virus, undegraded molecules form a sharp peak with a molecular weight corresponding to the total RNA content of the virus particle. Degradation kinetics by ribonuclease is of the linear, single-target type, indicating that the RNA is single-stranded. The intact RNA of a virus particle thus forms one big single-stranded molecule. Quantitative evaluation of the effect degradation by RNA-ase on the infectivity of the RNA shows that the integrity of the entire molecule is required for its biological activity.
Ancient Greek philosophers were the first to postulate the possibility of explaining nature in theoretical terms and to initiate attempts at this. With the rise of monotheistic religions of revelation claiming supremacy over human reason and envisaging a new world to come, studies of the natural order of the transient world were widely considered undesirable. Later, in the Middle Ages, the desire for human understanding of nature in terms of reason was revived. This article is concerned with the fundamental reversal of attitudes, from “undesirable” to “desirable”, that eventually led into the foundations of modern science. One of the earliest, most ingenious and most interesting personalities involved was Eriugena, a theologian at the Court of Charles the Bald in the 9th century. Though understanding what we call nature is only one of the several aspects of his theological work, his line of thought implies a turn into a pro-scientific direction: the natural order is to be understood in abstract terms of ‘primordial causes’; understanding nature is considered to be the will of God; man encompasses the whole of creation in a physical as well as a mental sense. Basically similar ideas on the reconciliation of scientific rationality and monotheistic religions of revelation were conceived, independently and nearly simultaneously, by the Arab philosopher al-Kindi in Bagdad. Eriugena was more outspoken in his claim that reason is superior to authority. This claim is implicit in the thought of Nicholas of Cusa with his emphasis on human mental creativity as the image of God’s creativity; and it is the keynote of Galileo’s ‘Letter to the Grand Duchess Christina’ some 800 years later, the manifesto expressing basic attitudes of modern science. This article in English is based on the monography (in German): A. Gierer “Eriugena, al-Kindi, Nikolaus von Kues - Protagonisten einer wissenschaftsfreundlichen Wende im philosophischen und theologischen Denken”, Acta Historica Leopoldina 29 (1999), Barth Verlag in MVH Verlage Heidelberg, ISBN: 3-335-00652-6
Applying mild methods of preparation, part of the ribosomes of rabbit reticulocytes are found in aggregates (later called polyribosomes) of up to six ribosomal units. Upon treatment with RNA-ase, they desintegrate into single ribosomes. The fast-sedimenting aggregates are found to be more active in protein synthesis in terms of incorporation of radioactive amino acids, whereas the single ribosomes are more receptive to stimulation by the artificial messenger RNA poly-U. The findings indicate that the linkage of ribosomes into aggregates is due to the messenger RNA. They support a tape-reading mechanism of protein synthesis whereby growth of the peptide chain is accompanied by shifting the active site of the ribosome from one coding group of nucleotides of the messenger RNA to the next.
This is the invited evening lecture of the biannual workshop on hydroid development of 1999. Its topic is the role of hydra as a rather puristic model for the de-novo generation of spatial patterns in development, and our work in this field. Emphasis is placed not only on experimental studies, but also on theoretical analysis, because the understanding of spatial order requires a systems approach involving the combination of knowledge on molecules, cells and tissues with mathematical analysis, laws and facts.
Understanding cooperative human behaviour depends on insights into the biological basis of human altruism, as well as into socio-cultural development. In terms of evolutionary theory, kinship and reciprocity are well established as underlying cooperativeness. Reasons will be given suggesting an additional source, the capability of a cognition-based empathy that may have evolved as a by-product of strategic thought. An assessment of the range, the intrinsic limitations, and the conditions for activation of human cooperativeness would profit from a systems approach combining biological and socio-cultural aspects. However, this is not yet the prevailing attitude among contemporary social and biological scientists who often hold prejudiced views of each other's notions. It is therefore worth noticing that the desirable integration of aspects has already been attempted, in remarkable and encouraging ways, in the history of thought on human nature. I will exemplify this with the ideas of the fourteenth century Arab-Muslim historian Ibn Khaldun. He set out to explicate human cooperativeness - "asabiyah" - as having a biological basis in common descent, but being extendable far beyond within social systems, though in a relatively unstable and attenuated fashion. He combined psychological and material factors in a dynamical theory of the rise and decline of political rulership, and related general social phenomena to basic features of human behaviour influenced by kinship, expectation of reciprocity, and empathic emotions.
Full applicability of physics to human biology does not necessarily imply that one can uncover a comprehensive, algorithmic correlation between physical brain states and corresponding mental states. The argument takes into account that information processing is finite in principle in a finite world. Presumbly the brain-mind-relation cannot be resolved in all essential aspects, particularly when high degrees of abstraction or self-analytical processes are involved. Our conjecture plausibly unifies the universal validity of physics and a logical limitation of human thought, and it does not regard consciousness -the most basic human experience - as a marginal phenomenon. ++++ RATIO appeared up to 1987 in both a German and an English version. The German title of this article: Alfred Gierer, Der physikalische Grundlegungsversuch in der Biologie und das psychophysische Problem. RATIO XII, Heft 1, 1970, S. 40-54.
Modern brain research related to consciousness has resulted in many interesting in- sights, for example into the neurobiological basis of attention and of language. In biological terms, human consciousness appears as a system’s feature of our brain, with neural processes strictly following the laws of physics. This does not necessarily imply, however, that there can be a general and comprehensive scientific theory of consciousness. Predictions of the extent to which such a theory may become possi- ble vary widely in the scientific community. There are reasons - not only practical but also epistemological - why the brain-mind relation may not be fully decodable by finite procedures. In particular, analogies with mathematical theorems of un- decidability suggest that self-referential features of consciousness, such as multiple self-representations like those involved in strategic thought, may not be fully resolv- able by brain analysis. Assuming such limitations exist, this implies that ob jective analysis cannot exhaust sub jective experience in principle. A person’s consciousness and will are accessible to external observation only within limits. In some respects, we do not even learn to know ourselves except by our actions. It thus appears that a scientific look at consciousness and the human mind, combining universal physi- calism with epistemological scepticism, is not inconsistent with certain concepts of sub jectivity that are current in the humanities, despite all the differences in the style and terminology of discourse.
Socioeconomic inequalities are functions not only of intrinsic differences between persons or groups, but also of the dynamics of their interactions. Inequalities can arise and become stabilized if there are advantages (such as generalized wealth including “human capital”) which are self-enhancing, whereas depletion of limiting resources is widely distributed. A recent theory of biological pattern formation has been generalized, adapted and applied to deal with this process. Applications include models for the non-Gaussian distribution of personal income and wealth, for overall economic growth in relation to inequalities and for effects of uncoupling strategies between developing and developed countries. Note added after publication: The equations (14) for the model of the income distribution, with its characteristic non-Gaussian extension towards higher incomes (fig.4), are closely related to the Fokker-Planck equation that is widely applied in many fields of physics.
The introductory personal remarks refer to my motivations for choosing research projects, and for moving from physics to molecular biology and then to development, with Hydra as a model system. Historically, Trembley’s discovery of Hydra regeneration in 1744 was the begin¬ning of developmental biology as we understand it, with passionate debates about preformation versus de novo generation, mechanisms versus organisms. In fact, seemingly conflicting bottom-up and top-down concepts are both required in combination to understand development. In modern terms, this means analysing the molecules involved, as well as searching for physical principles underlying development within systems of molecules, cells and tissues. During the last decade, molecular biology has provided surprising and impressive evidence that the same types of mol¬ecules and molecular systems are involved in pattern formation in a wide range of organisms, including coelenterates like Hydra, and thus appear to have been “invented” early in evolution. Likewise, the features of certain systems, especially those of developmental regulation, are found in many different organisms. This includes the generation of spatial structures by the interplay of self-enhancing activation and “lateral” inhibitory effects of wider range, which is a main topic of my essay. Hydra regeneration is a particularly clear model for the formation of defined patterns within initially near-uniform tissues. In conclusion, this essay emphasizes the analysis of development in terms of physical laws, including the application of mathematics, and insists that Hydra was, and will continue to be, a rewarding model for understanding general features of embryogenesis and regeneration.
The short paper introduces the concept of possible branches of double-stranded DNA (later sometimes called palindromes): Certain sequences of nucleotides may be followed, after a short unpaired stretch, by a complementary sequence in reversed order, such that each DNA strand can fold back on itself, and the DNA assumes a cruciform or tree-like structure. This is postulated to interact with regulatory proteins.
The climate change debate has increased the need for knowledge on both long- and short-term regional environmental changes. In general, these changes may often be a product of multiple causes, which complicates the separation of single driving forces. In this review we focus on current water budget changes in Germany’s capital region, Berlin-Brandenburg, over the last 30 years. Available studies from a variety of disciplines (e.g. hydrology, water engineering, landscape ecology, nature conservation) were analysed in order to (1) identify both local and regional hydrological changes, (2) reveal their potential causes, and (3) discuss responses of ecosystems and society. These studies show that the Berlin-Brandenburg region is widely characterised by decreasing groundwater recharge, leading to decreasing groundwater and lake levels as well as decreasing fluvial discharge. These trends result both from complex, regional human impacts (e.g. long-term effects of hydro-melioration and changes in forest composition) and more general climate warming. The observed and assumed (future) changes of the regional water balance have been creating, and will continue to create, multifaceted impacts on existing ecosystems and society (e.g. wetland drying, decrease of biodiversity, decrease of productivity of grasslands and forests, increasing conflicts of interests). Several efforts to respond to the regional water deficit problem have already been undertaken, comprising for instance land-use optimisation, wetland restoration measures and the reestablishment of mixed deciduous forests. In general, however, the reviewed regional material on this topic reveals that the number and complexity of empirical studies are still poor. Thus, for both the identification and the explanation of current water balance changes and their effects, as well as for development and implementation of adaptive strategies, further multidisciplinary research efforts at different scales, including interregional comparisons, are required. Furthermore, both the observation of hydrological changes and the evaluation of adaptive and mitigative responses require at least continuous or, even better, extended monitoring efforts.
This special issue of DIE ERDE presents selected key topics discussed within the BBAW working group, including work by group members and invited external researchers, containing nine articles highlighting “Regional Water Challenges” resulting from different kinds of environmental and social changes. We aim to present the complexity of interaction between changes and responses. While the first four articles focus on describing climatic and hydrological changes and their causes, the following five articles focus more on possible mitigation and adaptation measures.
Für Schleiermacher ist Religion keine pädagogisch nützliche Mischung von Metaphysik und Moral, sondern eine eigene Dimension des Menschseins, Anschauung des Universums, Sinn und Geschmack fürs Unendliche; die von der Aufklärung favorisierte „natürliche Religion“ der allgemeinen, übergeschichtlichen Vernunftwahrheiten sei bloß eine Totgeburt, jede wirkliche, lebendige Religion dagegen eine unableitbare geschichtliche Individualität. Im Christentum sei Jesus Christus die Zentralgestalt, der Vermittler und Versöhner des Zwiespalts zwischen Endlichem und Unendlichem, an dem sich alle Religion abarbeite. Im Laufe seiner Entwicklung strebe das Christentum immer mehr zu Sozialgestalten ohne Hierarchie zwischen Priestern und Laien; in der Vollendung (den aber selbst der Protestantismus noch nicht erreicht habe) würden alle „von Gott gelehrt“ sein (Johannes 6,45).
Der theologische Rationalismus war die letzte Gestalt der Aufklärungstheologie; seine Blütezeit erlebte er gleichzeitig und in Konkurrenz mit der u.a. von Schelling geprägten spekulativen Richtung und mit der teils mehr biblizistischen, teils mehr konfessionellen Theologie der Erweckung. Kennzeichen des Rationalismus war einerseits eine verstärkte historisch-kritische Quellenforschung, andererseits das Bemühen, Lehre und Praxis soweit möglich auf das auszurichten, was jenseits geschichtlicher Autoritäten der allgemeinen menschlichen Vernunft plausibel sei: die Existenz Gottes, die Unsterblichkeit der Seele und die Pflicht zu tugendhaftem Leben. Seit etwa 1840 verfiel der Rationalismus.
The neuronal dynamics of auditory language comprehension : (Akademievorlesung am 12. November 1998)
(1999)
With the present report the Berlin-Brandenburg Academy of Sciences and Humanities wants to draw attention to the results of one of its interdisciplinary projects, which are published elsewhere in more detail. The authors believe that their particular approach to the subject of "waste energy recovery", in combination with an interdisciplinary perspective, suggests a new way of discussing energy problems that has the potential to lead to qualified statements...
We expose analogies between turbulence in a fluid heated from below (Rayleigh-Bénard (RB) flow) and shear flows: The unifying theory for RB flow (S.Grossmann and D.Lohse, J.Fluid Mech. 407, 27-56 (2000) and subsequent refinements) can be extended to the flow between rotating cylinders (Taylor-Couette flow) and pipe flow. We identify wind dissipation rates and momentum fluxes that are analogous to the dissipation rate and heat flux in RB flow. The proposed unifying description for the three cases is consistent with the experimental data.
The present study explores whether regional water resources can be used more efficiently by Brandenburg’s farming systems. A description of agriculture in Brandenburg today is followed by a systematic analysis of measures to raise the water efficiency. Brandenburg’s agricultural systems are divided into three sections: soil, plant production and livestock farming. Within these sections measures to increase water efficiency are listed and analysed with reference to five objective criteria for raising water use efficiency. In view of the complexity of farming systems in Brandenburg, general measures to raise water use efficiency could not be derived. Site-specific tillage practices and crop patterns adjusted to recent weather conditions may reflect the specific diversity of Brandenburg more efficiently.
Alexander von Humboldt’s maps, graphs and illustrations contain a great deal of detail, but in the available rare editions they are hardly visible to the naked eye. In many editions they have been reduced. In a digital library, they will become accessible in their entirety, and Internet technology will reproduce them in a form that overcomes the limitations of the original printing. The user will be able to enlarge the images and see details that might have been overlooked in the past. The Humboldt’s digital library will adhere to the standards for digital libraries established by the Open Archives Initiative (OAI) and the tools EPRINTS and DSPACE to provide the Web services and determine the most effective way to establish dynamic linking and knowledge based searching of information within the archive.
Historic parks and gardens survive in many places with some sites still in use but others abandoned long ago and now given over to other purposes. Accurate repair and reliable reconstruction depend upon archaeological information which is particularly vulnerable to the effects of climate change. The impairment and loss of such detail threaten historical integrity. This means that we must monitor changes and develop suitable mitigation.
Global climate change and aspects of regional climate change in the Berlin-Brandenburg region
(2011)
To obtain an estimate of the average temperature of the northern hemisphere during the last 1200 years, proxy data have been merged with instrumental recordings. These instrumental measurements are, with a few exceptions, only available for the recent 150 years. In the city of Berlin the temperature has been recorded since as early as 1701. However, during the first 150 years the measurements were problematic as location, measurement procedure and instruments changed frequently and without proper documentation. From 1847 onwards observations became more reliable once the Royal Prussian Meteorological Institute had been established. For the last 100 years temperature and precipitation measurements have been performed in parallel at Berlin-Dahlem and Potsdam. The datasets recorded in the city of Berlin and in Berlin-Dahlem have been merged to obtain a record of more than 300 years. It indicates that the temperature of Berlin has risen by 1.04°C during the last 100 years after correcting for the urbanisation effect. In the same period, the total number of frost days has significantly decreased by almost 17 days, and the number of summer days has significantly increased by about 12 days. Annual mean precipitation has hardly changed (decrease less than 0.2 %) during the last century. However, rainfall has decreased by about 4 % in summer and increased by 3 % in winter. All precipitation changes are below the 95 % ignificance level. Model projections indicate that warming will continue which means that Berlin-Brandenburg will experience a temperature rise of about 3-3.5°C by the end of this century for the IPCC scenario A1B. For the same scenario precipitation is expected to increase by 10-20 % in winter and to decrease by 10-30 % in summer: The seasonal precipitation changes compensate each other resulting in an almost unchanged annual mean.
Alexander von Humboldt’s descriptions of volcanic mountains in his travel journals (Reise auf dem Río Magdalena, durch die Anden und Mexico) show both his reliance on and impatience with literary conventions and travel narratives. Using Goethe’s Italienische Reise and Bürger’s Münchhausen as points of comparison for literary treatments of the volcano ascent, Humboldt’s process of writing is examined. Humboldt shows the failure of the existing discourse and begins to experiment with narratives which fragment and recombine personal and historical modes of writing with, in this case, images from new technical inventions which visualize landscape according to fundamental scientific principles. While the inclusion of scientific prose is relevant, Humboldt’s link to modernity is based on experimental narrative techniques which draw upon changing sets of discourse practices to describe complex realities.
Some drawings from the >Paper Museum< of Cassiano dal Pozzo and the Berlin Codex Destailleur >D<
(2004)
The recent discoveries of the Czech mission show clearly that Abusir formed with Saqqara a single geographical unit in ancient Egypt and that the modern separation of them is outdated. Abusir seems to have played the crucial role as the last area into which the necropolis expanded after exhausting the space occuppied by the Archaic Cemetery of North Saqqara. In fact, it is the last vestige before the move from the area (including Dahshur and Meidum) to Giza at the beginning of the Fourth Dynasty. The tombs of Hetepi and lty, discovered and explored during the past few years, are probably the final representatives of genuine Third Dynasty tomb evolution in the Saqqara-Abusir area which drew its last breath at the beginning of the Fourth Dynasty. These tombs undoubtedly belonged to the upper class in the society of the day, though certainly not to members of the royal family. Their characteristics clearly show exactly what preceded later tomb development at Meidum, Dahshur and Giza.
The computer has come to play a transformative role in the ways we model, store, process and study text. Nevertheless, we cannot yet claim to have realised the promises of the digital medium: the organisation and dissemination of scholarly knowledge through the exchange, reuse and enrichment of data sets. Despite the acclaimed interdisciplinary nature of digital humanities, current digital research takes place in a closed environment and rarely surpasses the traditional boundaries of a field. Furthermore, it is worthwhile to continue questioning the models we use and whether they are actually suitable for our scholarly needs. There’s a risk that the affordances and limitations of a prevailing model may blind us to aspects it doesn’t support.
In her talk, Elli Bleeker discusses different technologies to model data with respect to their expressive power and their potential to address the needs of the scholarly community. Within this framework, she introduces a new data model for text, Text-As-Graph (TAG), and it’s reference implementation Alexandria, a text repository system. The TAG model allows researchers to store, query, and analyse text that is encoded from different perspectives. Alexandria thus stimulates new ways of looking at textual objects, facilitates the exchange of information across disciplines, and secures textual knowledge for future endeavours. From a philosophical perspective, the TAG model and the workflow of Alexandria raise compelling questions about our notions of textuality, and prompt us to reconsider how we can best model the variety of textual dimensions.